Impacto do uso de dieta imunomoduladora e dieta enteral em adultos, durante a quimioterapia e radioterapia em pacientes com câncer de cabeça e pescoço: uma revisão da literatura
Diet use of immunomodulatory impact and enteral diet in adults during chemotherapy and radiotherapy in patients with head and neck cancer: a literature review
Juliana Alves de Souza, Carin Weirich Gallon
Resumo
Objetivo: Analisar, a partir de evidências científicas, se o uso de imunonutrição é benéfico para pacientes com câncer de cabeça e pescoço. Método: Revisão de literatura, a partir da base de dados Academic Google, com a seguinte frase: Diet immunonutrition in head and neck cancer. A consulta à base de dados foi realizada durante o período janeiro a agosto de 2016. Os critérios de inclusão foram: últimos cinco anos, em seres humanos, artigos originais, inglês, português, espanhol; adultos e idosos entre 18 e 89 anos. Foram lidos na íntegra 17 artigos e selecionados para esta revisão 11 artigos. Dentre estes, 10 estudos tiveram consenso para o uso de imunonutrição de arginina e ácidos graxos ômega 3 em relação aos benefícios para pacientes com câncer de cabeça e pescoço, enquanto um não encontrou resultados significativos. Resultados: Observamos melhora no estado imunológico e inflamatório, a prevenção de mucosite, principalmente nos pacientes com tratamento de quimioterapia e radioterapia com uso de imunonutrição de arginina e ômega 3 no câncer de cabeça e pescoço. Conclusão: Evidencia-se a importância do acompanhamento nutricional, do início até o final do tratamento, em pacientes com câncer de cabeça e pescoço por desenvolver perda de peso importante com causas multifatoriais, aumentando o risco nutricional, morbidade e mortalidade.
Palavras-chave
Abstract
Objective: To analyze, from scientific evidences, if the use of immunonutrition is beneficial for patients with head and neck cancer. Methods: A literature review from the Academic Google database, using the following phrase: Diet immunonutrition in head and neck cancer. The query the database was conducted during the period from January to August 2016. The criteria inclusion were the last five years, in humans, original articles, in English, Portuguese, Spanish and adults and the elderly of 18-89 years. They were read in full 17 articles and selected for this review, 11 articles. Among the findings, 10 of the 11 studies had consensus for the use of immunonutrition arginine and ômega 3 fatty acids in relation to the benefits for patients with head and neck cancer, while one did not find significant results. Results: We observed an improvement in the imune and inflammatory state, prevention of mucositis in patients primarily with chemotherapy and radiation therapy with the use of immunonutrition, arginine and ômega 3 in head and neck cancer. Conclusion: Therefore, highlights the importance of nutritional monitoring from the beginning to the end of treatment in patients with head and neck cancer by developing important weight loss; the causes are multifactorial increasing nutritional risk, morbidity and mortality.
Keywords
Referências
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Submetido em:
05/04/2017
Aceito em:
26/06/2017
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