Avaliação da função renal em pacientes admitidos em um hospital universitário de Recife-PE
Assessment of renal function in adult patients admitted to an university hospital in Recife-PE
Priscila Vieira Antunes, Poliana Coelho Cabral, Danielli Belém Cavalcanti, Emília Karol Carvalho de Lima
Resumo
Introdução: A doença renal crônica é um problema de saúde pública mundial. Recomenda-se o monitoramento da taxa de filtração glomerular (TFG) para avaliação da função renal (FR), pois sua redução precede a sintomatologia. Método: Estudo transversal, realizado com pacientes admitidos no Hospital das Clínicas de Pernambuco, no período de março a agosto de 2015. Foram consideradas variáveis demográficas, clínicas, bioquímicas e antropométricas. A TFG foi estimada pelas fórmulas Modification of Diet in Renal Disease (MDRD) e Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). Para verificar as possíveis associações entre as variáveis, foi utilizada a TFG pelo CKD-EPI, considerando alteração da FR TFG<60 mLmin/1,73m². Resultados: Foram avaliados 272 pacientes, 53,3% do sexo masculino, 48,5% de pardos, 62% não apresentavam afecções associadas. Quanto à antropometria, 9,9% possuíam índice de massa corporal <18,5 kg/m² e 28,3%, >24,9 kg/m². A idade média foi de 50±16,4 anos e 4,0% com TFG <60 ml/min/1,73m2 com a MDRD e 11,4% pela CKD-EPI. A idade avançada e comorbidades associaram-se positivamente com a redução da TFG (p=0,000). Conclusão: O CKD-EPI mostrou pacientes com déficit da FR, o que se torna um alerta, pois são indivíduos sem diagnóstico prévio.
Palavras-chave
Abstract
Introduction: Chronic kidney disease is a worldwide public health problem. It is recommended to monitor the glomerular filtration rate (GFR) for assessment of renal function (RF), because its reduction precedes symptoms. Objective: To identify the frequency of change in GFR and associated factors. Methods: Cross-sectional study on patients admitted to the Hospital das Clínicas de Pernambuco from March to August 2015. Demographic, clinical, biochemical and anthropometric variables were considered. The GFR was estimated by formulas Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and to verify the possible associations among variables was used the GFR by CKD-EPI considering FR changing GFR < 60 mLmin /1.73 m². Results: We evaluated 272 patients, 53.3% male, 48.5% brown-skinned, 62% had no associated pathologies. Regarding the anthropometry, 9.9% had a body mass index <18.5 kg / m² and 28.3%> 24.9kg / m². The average age was 50±16.4 years and 4% with GFR <60 ml/min/1.73m2 with MDRD and 11.4% for CKD-EPI. Advanced comorbidities age was positively associated with the GFR reduction (p=0.000). Conclusion: The CKD-EPI found patients with FR deficit, which becomes an alert, for being individuals without previous diagnosis.
Keywords
Referências
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Submetido em:
23/05/2016
Aceito em:
31/07/2016
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